Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50042058
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017103(9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenyli...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50001285((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017691(CHEMBL126075 | dilazep)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017103(9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenyli...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMedDrugBank
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50001285((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50017691(CHEMBL126075 | dilazep)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM23617((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(4-nitrophe...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed