Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 50042167
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104526(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104531(3-[3-((S)-1-{2-[3-Methoxy-4-(3-o-tolyl-ureido)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104531(3-[3-((S)-1-{2-[3-Methoxy-4-(3-o-tolyl-ureido)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104529((S)-1-{2-[(S)-(R)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104530(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104529((S)-1-{2-[(S)-(R)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104533(3-[5-(2-Carboxy-ethyl)-3-((S)-3-methyl-1-{2-[4-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104536((R)-3-(2,6-Dichloro-benzoylamino)-4-(2',6'-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104531(3-[3-((S)-1-{2-[3-Methoxy-4-(3-o-tolyl-ureido)-phe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104526(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104527(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104534(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104530(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104534(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104533(3-[5-(2-Carboxy-ethyl)-3-((S)-3-methyl-1-{2-[4-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104527(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104529((S)-1-{2-[(S)-(R)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104536((R)-3-(2,6-Dichloro-benzoylamino)-4-(2',6'-dimetho...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104534(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 143nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104530(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 171nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104526(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104533(3-[5-(2-Carboxy-ethyl)-3-((S)-3-methyl-1-{2-[4-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 347nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104527(3-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 495nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104528(4-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104532(CHEMBL84739 | [2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104535(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104528(4-[3-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104535(3-[2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-ureido)-phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50104537(CHEMBL86424 | [2-((S)-3-Methyl-1-{2-[4-(3-o-tolyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41SQZPubMed