Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50042232
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157445(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157461(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157458(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157446(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157464(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157470(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157475(3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157447(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157459(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157469(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157466(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157463(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157465(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157443(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50117056((S)-2-(2-Bromo-6-methyl-benzoylamino)-3-[4-(2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157474(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157467(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157455(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM16801((2S)-2-[(2,6-dichlorophenyl)formamido]-3-[4-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157444(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157450(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157448(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(3,...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157456(2-{3-[(Cyclohex-3-enecarbonyl)-isobutyl-amino]-phe...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157471(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(iso...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157468(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157457(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[iso...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157476(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157449(2-[3-(Benzoyl-isobutyl-amino)-phenyl]-3-[4-(2,6-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157462(2-[3-(Acetyl-isobutyl-amino)-phenyl]-3-[4-(2,6-dic...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157473(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-[3-(met...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157452(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(3-{iso...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157453(2-{3-[Benzyl-(2,2-dimethyl-propionyl)-amino]-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157454(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-{3-[(fu...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157460(2-[3-(tert-Butoxycarbonyl-isobutyl-amino)-phenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157472(3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(3-phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Kaken Pharmaceutical Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50157451(2-{3-[(Cyclohex-3-enecarbonyl)-amino]-phenyl}-3-[4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Very late antigen-4 (VLA-4) expressing human leukemia cells (HL-60) aggregation with human Vascular cell adhesion molecule-1 (VCAM-1) e...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945Z1PubMed