Compile Data Set for Download or QSAR
Found 91 Enz. Inhib. hit(s) with all data for entry = 50042367
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424785(CHEMBL2315102)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424785(CHEMBL2315102)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424790(CHEMBL2315095)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424789(CHEMBL2315096)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424823(CHEMBL2315110)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424802(CHEMBL2315130)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424800(CHEMBL2315132)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424802(CHEMBL2315130)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424818(CHEMBL2315115)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304937(CHEMBL591796 | N-phenethyl-6-(4-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304937(CHEMBL591796 | N-phenethyl-6-(4-(2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424800(CHEMBL2315132)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424786(CHEMBL2315101)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424787(CHEMBL2315100)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424794(CHEMBL2315412)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424826(CHEMBL2315107)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424787(CHEMBL2315100)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424794(CHEMBL2315412)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50301062(CHEMBL572098 | N-(2-cyclopropylethyl)-6-(4-(2-(tri...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424788(CHEMBL2315099)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424788(CHEMBL2315099)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424817(CHEMBL2315116)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424821(CHEMBL2315112)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424822(CHEMBL2315111)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424797(CHEMBL2315135)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424790(CHEMBL2315095)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50301062(CHEMBL572098 | N-(2-cyclopropylethyl)-6-(4-(2-(tri...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424826(CHEMBL2315107)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424795(CHEMBL2315137)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424803(CHEMBL2315129)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424809(CHEMBL2315124)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424795(CHEMBL2315137)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424818(CHEMBL2315115)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424828(CHEMBL2315105)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424823(CHEMBL2315110)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424809(CHEMBL2315124)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424793(CHEMBL2315089)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424784(CHEMBL2315103)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424789(CHEMBL2315096)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424793(CHEMBL2315089)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424797(CHEMBL2315135)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424815(CHEMBL2315118)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
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