Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 50042591
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataIC50: 2.22E+3nMAssay Description:Antagonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428278(CHEMBL446306)copy SMILEScopy InChI
Affinity DataIC50: 9.76E+3nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428276(CHEMBL2337487)copy SMILEScopy InChI
Affinity DataIC50: 5.86E+4nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428275(CHEMBL2337889)copy SMILEScopy InChI
Affinity DataIC50: 7.65E+4nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428276(CHEMBL2337487)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428275(CHEMBL2337889)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428277(CHEMBL2337486)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50428277(CHEMBL2337486)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+5nMAssay Description:Antagonist activity at human GABAC rho1 receptor expressed in Xenopus laevis oocytes assessed as inhibition of GABA-induced current by two electrode ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50218536(4(5)-(carboxymethyl)-5(4)-methylimidazole | CHEMBL...)copy SMILEScopy InChI
Affinity DataEC50:  2.20E+4nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM23183(5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL2...)copy SMILEScopy InChI
Affinity DataEC50:  2.30E+3nMAssay Description:Partial agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50241194((1S,2R)-2-(aminomethyl)cyclopropanecarboxylic acid...)copy SMILEScopy InChI
Affinity DataEC50:  3.97E+4nMAssay Description:Agonist activity at GABAC rho1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KXGPubMed