Found 74 Enz. Inhib. hit(s) with all data for entry = 50042688 TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 178nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 205nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 211nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 445nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 492nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 582nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 672nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 674nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 760nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 1.25E+3nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 1.28E+3nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 1.54E+3nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataKi: 3.79E+3nMAssay Description:Displacement of [3H]-ABP688 from human mGluR5 expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 228nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 231nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 266nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 314nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 425nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 468nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 473nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 531nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 593nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 612nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 647nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 671nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 789nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 857nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at rat mGluR1 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.91E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Lundbeck Research USA, Inc.
Curated by ChEMBL
Lundbeck Research USA, Inc.
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
