Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with all data for entry = 50043562
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50425950(CHEMBL2311561 | Isoniazid-NAD)copy SMILEScopy InChI
Affinity DataKi:  0.75nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442997(CHEMBL3088172)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443004(CHEMBL3088173)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443005(CHEMBL3088171)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443007(CHEMBL1236225 | PT70)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443002(CHEMBL3088175)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443001(CHEMBL3088176)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443003(CHEMBL3088174)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442999(CHEMBL3087016)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443000(CHEMBL3087015)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443006(CHEMBL3088170)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50443008(Pyridomycin)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of wild type Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442998(CHEMBL3087017)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB4769PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442997(CHEMBL3088172)copy SMILEScopy InChI
Affinity DataKd:  14nMAssay Description:Binding affinity to Mycobacterium tuberculosis NADH-bound form full length inhA (1 to 255) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442997(CHEMBL3088172)copy SMILEScopy InChI
Affinity DataKd:  12nMAssay Description:Binding affinity to Mycobacterium tuberculosis NADH-bound form of full length inhA (1 to 255) by SPR assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50442997(CHEMBL3088172)copy SMILEScopy InChI
Affinity DataKd:  9.30E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis NAD+-bound form of full length inhA (1 to 255) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair