Compile Data Set for Download or QSAR
Found 50 Enz. Inhib. hit(s) with all data for entry = 50043679
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444550(CHEMBL3099704)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444552(CHEMBL3099689)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444565(CHEMBL3099604)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444564(CHEMBL3099682)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444561(CHEMBL3099687)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444551(CHEMBL3099683)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444552(CHEMBL3099689)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444559(CHEMBL3099690)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444555(CHEMBL3099694)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444551(CHEMBL3099683)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444554(CHEMBL3099697)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444556(CHEMBL3099693)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444563(CHEMBL3099684)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444553(CHEMBL3099686)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444570(CHEMBL3099699)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444551(CHEMBL3099683)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetAromatase(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444553(CHEMBL3099686)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human CYP19 preincubated for 10 mins followed by protein addition measured after 90 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444571(CHEMBL3099698)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444569(CHEMBL3099700)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444557(CHEMBL3099692)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444560(CHEMBL3099688)copy SMILEScopy InChI
Affinity DataIC50: 351nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 386nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444566(CHEMBL3099703)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444558(CHEMBL3099691)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444567(CHEMBL3099702)copy SMILEScopy InChI
Affinity DataIC50: 464nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 495nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444562(CHEMBL3099685)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 686nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444568(CHEMBL3099701)copy SMILEScopy InChI
Affinity DataIC50: 792nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetAromatase(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444551(CHEMBL3099683)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CYP19 preincubated for 10 mins followed by protein addition measured after 90 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetAromatase(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP19 preincubated for 10 mins followed by protein addition measured after 90 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetAromatase(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP19 preincubated for 10 mins followed by protein addition measured after 90 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed