Compile Data Set for Download or QSAR
Found 82 Enz. Inhib. hit(s) with all data for entry = 50043880
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMedDrugBank
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447886(CHEMBL3114784)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447885(CHEMBL3114785)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447872(CHEMBL3114772)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447876(CHEMBL3114768)copy SMILEScopy InChI
Affinity DataIC50: 278nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447878(CHEMBL3114766)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50335231(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 311nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447866(CHEMBL3114778)copy SMILEScopy InChI
Affinity DataIC50: 408nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)copy SMILEScopy InChI
Affinity DataIC50: 423nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447868(CHEMBL3114776)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447882(CHEMBL3114762)copy SMILEScopy InChI
Affinity DataIC50: 497nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)copy SMILEScopy InChI
Affinity DataIC50: 564nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447879(CHEMBL3114765)copy SMILEScopy InChI
Affinity DataIC50: 576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447863(CHEMBL3114781)copy SMILEScopy InChI
Affinity DataIC50: 576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)copy SMILEScopy InChI
Affinity DataIC50: 625nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)copy SMILEScopy InChI
Affinity DataIC50: 628nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447875(CHEMBL3114769)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447884(CHEMBL3114786)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447873(CHEMBL3114771)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447865(CHEMBL3114779)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447864(CHEMBL3114780)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447883(CHEMBL3114761)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447867(CHEMBL3114777)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447869(CHEMBL3114775)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447877(CHEMBL3114767)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447872(CHEMBL3114772)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447870(CHEMBL3114774)copy SMILEScopy InChI
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447863(CHEMBL3114781)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)copy SMILEScopy InChI
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447885(CHEMBL3114785)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447887(CHEMBL3114783)copy SMILEScopy InChI
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center, Inc.

Curated by ChEMBL
LigandPNGBDBM50447882(CHEMBL3114762)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5B9JPubMed
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