Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 634nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair