Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with all data for entry = 50044505
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019329(CHEMBL1089318)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019329(CHEMBL1089318)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of catalytic activity of rat COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scint...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Mus musculus)
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019329(CHEMBL1089318)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of catalytic activity of mouse COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid sci...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019331(CHEMBL3289430)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019333(CHEMBL3289432)copy SMILEScopy InChI
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019332(CHEMBL3289431)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Mus musculus)
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019331(CHEMBL3289430)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of catalytic activity of mouse COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid sci...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019331(CHEMBL3289430)copy SMILEScopy InChI
Affinity DataKi:  1.58E+5nMAssay Description:Inhibition of catalytic activity of rat COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liquid scint...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019330(CHEMBL3289429)copy SMILEScopy InChI
Affinity DataKi:  2.51E+5nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019333(CHEMBL3289432)copy SMILEScopy InChI
Affinity DataKd:  2.51E+4nMAssay Description:Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019332(CHEMBL3289431)copy SMILEScopy InChI
Affinity DataKd:  6.31E+4nMAssay Description:Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019330(CHEMBL3289429)copy SMILEScopy InChI
Affinity DataKd:  2.51E+5nMAssay Description:Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed
TargetCatechol O-methyltransferase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50019331(CHEMBL3289430)copy SMILEScopy InChI
Affinity DataKd:  3.16E+4nMAssay Description:Binding affinity to NHS-PEG4-Biotin-labeled human COMT after 1 hr by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G9BPubMed