Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 50044575
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021350(CHEMBL3287940)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021352(CHEMBL3287943)copy SMILEScopy InChI
Affinity DataKi:  53nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021348(CHEMBL3287937)copy SMILEScopy InChI
Affinity DataKi:  57nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021353(CHEMBL3287944)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021355(CHEMBL3287946)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021351(CHEMBL3287942)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50434761(CHEMBL2385819)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021350(CHEMBL3287940)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021352(CHEMBL3287943)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021352(CHEMBL3287943)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50434763(CHEMBL2385817)copy SMILEScopy InChI
Affinity DataKi:  440nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021349(CHEMBL3287939)copy SMILEScopy InChI
Affinity DataKi:  490nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021348(CHEMBL3287937)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021349(CHEMBL3287939)copy SMILEScopy InChI
Affinity DataKi:  990nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021351(CHEMBL3287942)copy SMILEScopy InChI
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50434763(CHEMBL2385817)copy SMILEScopy InChI
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021353(CHEMBL3287944)copy SMILEScopy InChI
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021356(CHEMBL3287947)copy SMILEScopy InChI
Affinity DataKi:  2.34E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021354(CHEMBL3287945)copy SMILEScopy InChI
Affinity DataKi:  4.57E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021349(CHEMBL3287939)copy SMILEScopy InChI
Affinity DataKi:  9.11E+3nMAssay Description:Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50434761(CHEMBL2385819)copy SMILEScopy InChI
Affinity DataKi:  1.76E+4nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Universit£ degli Studi di Messina

Curated by ChEMBL
LigandPNGBDBM50021353(CHEMBL3287944)copy SMILEScopy InChI
Affinity DataKi:  2.37E+4nMAssay Description:Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09WCPubMed