Compile Data Set for Download or QSAR
Found 44 Enz. Inhib. hit(s) with all data for entry = 50044966
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038692(CHEMBL3354859)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038635(CHEMBL3354853)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038637(CHEMBL3354855)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038694(CHEMBL3354861)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038633(CHEMBL3354851)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038643(CHEMBL3354858)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038609(CHEMBL3354866)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038610(CHEMBL3354867)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038639(CHEMBL3354856)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038629(CHEMBL3354849)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038640(CHEMBL3354857)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038695(CHEMBL3354862)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038608(CHEMBL3354865)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038611(CHEMBL3354868)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038632(CHEMBL3354850)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038696(CHEMBL3354863)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038612(CHEMBL3354869)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038693(CHEMBL3354860)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038636(CHEMBL3354854)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038634(CHEMBL3354852)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038618(CHEMBL3354870)copy SMILEScopy InChI
Affinity DataIC50: 192nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038634(CHEMBL3354852)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038632(CHEMBL3354850)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038637(CHEMBL3354855)copy SMILEScopy InChI
Affinity DataIC50: 4.49E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038693(CHEMBL3354860)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038611(CHEMBL3354868)copy SMILEScopy InChI
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038636(CHEMBL3354854)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038696(CHEMBL3354863)copy SMILEScopy InChI
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038639(CHEMBL3354856)copy SMILEScopy InChI
Affinity DataIC50: 5.55E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038692(CHEMBL3354859)copy SMILEScopy InChI
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038618(CHEMBL3354870)copy SMILEScopy InChI
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038694(CHEMBL3354861)copy SMILEScopy InChI
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038612(CHEMBL3354869)copy SMILEScopy InChI
Affinity DataIC50: 6.53E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038640(CHEMBL3354857)copy SMILEScopy InChI
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038695(CHEMBL3354862)copy SMILEScopy InChI
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038629(CHEMBL3354849)copy SMILEScopy InChI
Affinity DataIC50: 6.71E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038633(CHEMBL3354851)copy SMILEScopy InChI
Affinity DataIC50: 7.32E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038643(CHEMBL3354858)copy SMILEScopy InChI
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038609(CHEMBL3354866)copy SMILEScopy InChI
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038608(CHEMBL3354865)copy SMILEScopy InChI
Affinity DataIC50: 8.55E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038635(CHEMBL3354853)copy SMILEScopy InChI
Affinity DataIC50: 8.95E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50038610(CHEMBL3354867)copy SMILEScopy InChI
Affinity DataIC50: 9.35E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068N3PubMed