Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 50045076
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62170(1-(4-chlorophenyl)sulfonyl-2-benzimidazolamine | 1...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044276(CHEMBL3321858)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044275(CHEMBL3321857)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62249(1-[5-[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65733(3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65733(3-methyl-8-nitro-7-(phenylmethyl)purine-2,6-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044271(CHEMBL3321853)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65729(3-methyl-7-pentyl-8-(2-phenylethylsulfanyl)purine-...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62249(1-[5-[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65731(3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purin...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044273(CHEMBL3321855)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM49106(7-[(E)-but-2-enyl]-3-methyl-8-(3-phenylpropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044272(CHEMBL3321854)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044270(CHEMBL3321852)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50044274(CHEMBL3321856)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62334(1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of NOD1 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62334(1-[(4-chlorophenyl)methyl]-2-benzimidazolamine | 1...)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM49106(7-[(E)-but-2-enyl]-3-methyl-8-(3-phenylpropylsulfa...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65731(3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purin...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM62170(1-(4-chlorophenyl)sulfonyl-2-benzimidazolamine | 1...)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM65729(3-methyl-7-pentyl-8-(2-phenylethylsulfanyl)purine-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed