Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50045374
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of full length human fusion His6 tagged PRL3 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by imm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of full length human fusion His6 tagged PRL1 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by imm...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of human PRL2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by immobilized metal ion affinity-bas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059140(CHEMBL3393148)copy SMILEScopy InChI
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059140(CHEMBL3393148)copy SMILEScopy InChI
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059140(CHEMBL3393148)copy SMILEScopy InChI
Affinity DataIC50: 3.14E+4nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059086(CHEMBL3393146)copy SMILEScopy InChI
Affinity DataIC50: 4.78E+4nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059085(CHEBI:8830 | Rhodanine)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059141(CHEMBL3393149)copy SMILEScopy InChI
Affinity DataIC50: 5.67E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059141(CHEMBL3393149)copy SMILEScopy InChI
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059141(CHEMBL3393149)copy SMILEScopy InChI
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059086(CHEMBL3393146)copy SMILEScopy InChI
Affinity DataIC50: 7.01E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059142(CHEMBL3393150)copy SMILEScopy InChI
Affinity DataIC50: 8.91E+4nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059139(CHEMBL3393147)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059086(CHEMBL3393146)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059142(CHEMBL3393150)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059142(CHEMBL3393150)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059143(CHEMBL3393151)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059143(CHEMBL3393151)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 3(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059143(CHEMBL3393151)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of PRL3 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059085(CHEBI:8830 | Rhodanine)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059139(CHEMBL3393147)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059139(CHEMBL3393147)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 1(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50059085(CHEBI:8830 | Rhodanine)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of PRL1 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed