BindingDB PrimarySearch

Found 16 Enz. Inhib. hit(s) with all data for entry = 50045653

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072961(CHEMBL3410672)copy SMILEScopy InChI

IC50: 1.5nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072963(CHEMBL3410548)copy SMILEScopy InChI

IC50: 5.80nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384248(CHEMBL2030451)copy SMILEScopy InChI

IC50: 28nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384247(CHEMBL2030436)copy SMILEScopy InChI

IC50: 288nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072962(CHEMBL3410675)copy SMILEScopy InChI

IC50: 562nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384248(CHEMBL2030451)copy SMILEScopy InChI

IC50: 562nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072964(CHEMBL3410642)copy SMILEScopy InChI

IC50: 759nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072961(CHEMBL3410672)copy SMILEScopy InChI

IC50: 912nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384255(CHEMBL1312643)copy SMILEScopy InChI

IC50: 1.41E+3nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072963(CHEMBL3410548)copy SMILEScopy InChI

IC50: 3.24E+3nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072961(CHEMBL3410672)copy SMILEScopy InChI

IC50: 5.50E+3nMAssay Description:Inhibition of recombinant PI3Kbeta (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072961(CHEMBL3410672)copy SMILEScopy InChI

IC50: 6.31E+3nMAssay Description:Inhibition of recombinant PI3Kgamma (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072964(CHEMBL3410642)copy SMILEScopy InChI

IC50: 7.94E+3nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50072961(CHEMBL3410672)copy SMILEScopy InChI

IC50: 9.33E+3nMAssay Description:Inhibition of recombinant PI3Kdelta (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384255(CHEMBL1312643)copy SMILEScopy InChI

IC50: 1.74E+4nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL

BDBM50384247(CHEMBL2030436)copy SMILEScopy InChI

IC50: 2.63E+4nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using biotinylated PIP2 as substrateMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2DF6SW8PubMed