Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50045970
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089252(CHEMBL3577889)copy SMILEScopy InChI
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089251(CHEMBL3576881)copy SMILEScopy InChI
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089248(CHEMBL3577881)copy SMILEScopy InChI
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089253(CHEMBL3577900)copy SMILEScopy InChI
Affinity DataKi: >1.52E+4nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)copy SMILEScopy InChI
Affinity DataKi: >1.59E+4nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089257(CHEMBL3577904)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089259(CHEMBL3577902)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089252(CHEMBL3577889)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089248(CHEMBL3577881)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Antagonist activity against human TRPM8 by single cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089256(CHEMBL3577905)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089246(CHEMBL3577883)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089254(CHEMBL3577907)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089253(CHEMBL3577900)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089255(CHEMBL3577906)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089262(CHEMBL3577898)copy SMILEScopy InChI
Affinity DataIC50: 288nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089251(CHEMBL3576881)copy SMILEScopy InChI
Affinity DataIC50: 307nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089258(CHEMBL3577903)copy SMILEScopy InChI
Affinity DataIC50: 328nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089297(CHEMBL3577886)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089267(CHEMBL3577893)copy SMILEScopy InChI
Affinity DataIC50: 446nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089249(CHEMBL3577880)copy SMILEScopy InChI
Affinity DataIC50: 837nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089247(CHEMBL3577882)copy SMILEScopy InChI
Affinity DataIC50: 951nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089283(CHEMBL3577890)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089265(CHEMBL3577895)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089266(CHEMBL3577894)copy SMILEScopy InChI
Affinity DataIC50: 3.25E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089274(CHEMBL3577891)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089298(CHEMBL3577884)copy SMILEScopy InChI
Affinity DataIC50: 3.62E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089294(CHEMBL3577888)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089260(CHEMBL3577901)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089296(CHEMBL3577887)copy SMILEScopy InChI
Affinity DataIC50: 6.17E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089263(CHEMBL3577897)copy SMILEScopy InChI
Affinity DataIC50: 6.86E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089273(CHEMBL3577892)copy SMILEScopy InChI
Affinity DataIC50: 7.82E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089264(CHEMBL3577896)copy SMILEScopy InChI
Affinity DataIC50: 9.36E+3nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089261(CHEMBL3577899)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50089250(CHEMBL3577879)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZBCPubMed