Found 14 Enz. Inhib. hit(s) with all data for entry = 50046507 Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate assessed as inhibition...More data for this Ligand-Target Pair
3D Structure (crystal)Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0480nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.0780nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 84nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 93nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 298nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University of Wellington
Curated by ChEMBL
Victoria University of Wellington
Curated by ChEMBL
Affinity DataKi: 750nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
