Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for entry = 50046694
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM36371(5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidaz...)copy SMILEScopy InChI
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM21973(1-Methyltryptophan, 1 | 2-amino-3-(1-methyl-1H-ind...)copy SMILEScopy InChI
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50072081(CHEMBL3407922)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50061916(3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetKynurenine 3-monooxygenase(Saccharomyces cerevisiae (strain ATCC 204508 / S28...)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126147(CHEMBL3629571)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of yeast KMOMore data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human TDOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50350248(CHEMBL1812545)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of human TDOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50061907((+/-)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric aci...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human KMOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126145(CHEMBL3629570)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126145(CHEMBL3629570)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50324539((S)-(-)-9-(4-aminopiperazin-1-yl)-8-fluoro-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat KAT-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of mouse TDOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50350248(CHEMBL1812545)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of mouse TDOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24663(2-(1H-imidazol-4-yl)phenol | 2-(1H-imidazol-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24664(2-(1H-imidazol-4-yl)benzene-1,3-diol | 2-(1H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24665(3-(1H-imidazol-4-yl)benzene-1-thiol | 3-(1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24666(4-(1H-imidazol-4-yl)benzene-1-thiol | 4-(1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126149(CHEMBL3629573)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of rat KAT-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24667(2-(1H-imidazol-4-yl)benzene-1-thiol | 2-(1H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126142(4-Phenylimidazole | CHEMBL14145 | US11053207, Comp...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)copy SMILEScopy InChI
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Rattus norvegicus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50126148(CHEMBL3629572)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of rat KAT-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50289137(6-Fluoro-3-((E)-2-pyridin-3-yl-vinyl)-1H-indole | ...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of mouse IDO1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 2(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24674(3-(1H-imidazol-4-yl)phenol | 3-(1H-imidazol-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 3.65E+5nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50350248(CHEMBL1812545)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of mouse IDO1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Colorado College

Curated by ChEMBL
LigandPNGBDBM24677(4-(1H-imidazol-4-yl)phenol | 4-(1H-imidazol-4-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C3FPubMed