Compile Data Set for Download or QSAR
Found 26 Enz. Inhib. hit(s) with all data for entry = 50047427
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166941(CHEMBL3797606)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166942(CHEMBL3798501)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166944(CHEMBL3799864)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166949(CHEMBL3798128)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166945(CHEMBL3798887)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166950(CHEMBL3799428)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166948(CHEMBL3799255)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166946(CHEMBL3800597)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM149410(US10434101, Compound I-10 | US11096942, Compound I...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166943(CHEMBL3797963)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166947(CHEMBL3799138)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50383274(CHEMBL1229592 | US10167264, WZ4002 | US9670213, WZ...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50383274(CHEMBL1229592 | US10167264, WZ4002 | US9670213, WZ...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166949(CHEMBL3798128)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166950(CHEMBL3799428)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166942(CHEMBL3798501)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166946(CHEMBL3800597)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166945(CHEMBL3798887)copy SMILEScopy InChI
Affinity DataIC50: 174nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM149410(US10434101, Compound I-10 | US11096942, Compound I...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166948(CHEMBL3799255)copy SMILEScopy InChI
Affinity DataIC50: 248nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166941(CHEMBL3797606)copy SMILEScopy InChI
Affinity DataIC50: 272nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166944(CHEMBL3799864)copy SMILEScopy InChI
Affinity DataIC50: 389nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 409nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166947(CHEMBL3799138)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166943(CHEMBL3797963)copy SMILEScopy InChI
Affinity DataIC50: 731nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9D0TPubMed