Compile Data Set for Download or QSAR
Found 97 Enz. Inhib. hit(s) with all data for entry = 50047485
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant RET expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant RET expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170218(CHEMBL3804952)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170223(CHEMBL3805330)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170217(CHEMBL3805114)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170215(CHEMBL3806261)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170171(CHEMBL3805029)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170216(CHEMBL3805956)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant FLT3 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant FLT3 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170219(CHEMBL3805074)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170166(CHEMBL3804921)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170168(CHEMBL3805865)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170167(CHEMBL3805891)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170174(CHEMBL3804941)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170167(CHEMBL3805891)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170223(CHEMBL3805330)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170224(CHEMBL3804972)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170172(CHEMBL3806240)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170168(CHEMBL3805865)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170223(CHEMBL3805330)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170166(CHEMBL3804921)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) T315I mutant expressed in baculovirus expression system us...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 272nMAssay Description:Inhibition of human recombinant FGFR2 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170171(CHEMBL3805029)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170215(CHEMBL3806261)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170218(CHEMBL3804952)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170167(CHEMBL3805891)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170168(CHEMBL3805865)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170223(CHEMBL3805330)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170217(CHEMBL3805114)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170216(CHEMBL3805956)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 kinase domain (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170218(CHEMBL3804952)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 672nMAssay Description:Inhibition of human recombinant PDGFRalpha expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170220(CHEMBL3805094)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 kinase domain (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using JH3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170166(CHEMBL3804921)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of BCR fused full length human recombinant N-terminal His-tagged ABL (2 to 1130 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 888nMAssay Description:Inhibition of human recombinant c-KIT expressed in insect cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of human recombinant FGFR2 expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170221(CHEMBL3806189)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50170222(CHEMBL3805771)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TF3PubMed
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