Compile Data Set for Download or QSAR
Found 186 Enz. Inhib. hit(s) with all data for entry = 50047765
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 0.450nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188898(CHEMBL3828636)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188892(CHEMBL3828492)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188636(CHEMBL3827296)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188726(CHEMBL3827865)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188729(CHEMBL3828180)copy SMILEScopy InChI
Affinity DataIC50: 0.970nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188900(CHEMBL3827738)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188725(CHEMBL3827650)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188758(CHEMBL3828408)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188897(CHEMBL3827281)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188890(CHEMBL3827794)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188893(CHEMBL3828747)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50189006(CHEMBL3826997)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188894(CHEMBL3827004)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188895(CHEMBL3827660)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system incubated for 1 hr by kinase-g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188903(CHEMBL3827612)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188889(CHEMBL3828289)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188896(CHEMBL3828628)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188909(CHEMBL3827317)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant HDAC1 (482 residues) by Color-de-Lys assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188640(CHEMBL3827780)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188906(CHEMBL3828482)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188899(CHEMBL3827517)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188959(CHEMBL3827894)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188637(CHEMBL3827814)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188891(CHEMBL3828518)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50188897(CHEMBL3827281)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155K0PubMed
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