Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for entry = 50047895
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196073(CHEMBL3919081)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196066(20-O-Acetylneoavarol | CHEMBL516014)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196071(CHEMBL3971802)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196070(CHEMBL3962935)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196064(CHEMBL521017)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196067(CHEMBL3893783)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196068(CHEMBL3892140)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242257(2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196065(CHEMBL3973897)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196072(3''-Amino-Avarone | CHEMBL464646)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FRHPubMed