Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of HDAC2 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC1 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2X06900PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2X06900PubMedDrugBank
MMDB
PDB
![3D 3D](/images/Docked_3d.png)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC3 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
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