Compile Data Set for Download or QSAR
Found 69 Enz. Inhib. hit(s) with all data for entry = 50048183
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50227631(2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207335(CHEMBL3961834)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207322(CHEMBL3916119)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207343(CHEMBL3931344)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM124296(US8759537, 33)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human mPGES-1 expressed in Escherichia coli Rosetta microsomes assessed as reduction in conversion of PGH2 to PGE2 incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207345(CHEMBL3944077)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207337(CHEMBL3926181)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207329(CHEMBL3984373)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207324(CHEMBL3898125)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207323(CHEMBL3897959)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207342(CHEMBL3935630)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207316(CHEMBL3925606)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207318(CHEMBL3895356)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207344(CHEMBL3926203)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207325(CHEMBL3920280)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207336(CHEMBL3932436)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207328(CHEMBL3909776)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207338(CHEMBL3935105)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207344(CHEMBL3926203)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207319(CHEMBL3949380)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207327(CHEMBL3987179)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207323(CHEMBL3897959)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207326(CHEMBL3891935)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207322(CHEMBL3916119)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207337(CHEMBL3926181)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207333(CHEMBL3956753)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207331(CHEMBL3980735)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant membrane bound mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 by measuring MDA and 12-HHT formation by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207317(CHEMBL3955759)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207320(CHEMBL3918689)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207324(CHEMBL3898125)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207318(CHEMBL3895356)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207329(CHEMBL3984373)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207316(CHEMBL3925606)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207328(CHEMBL3909776)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207342(CHEMBL3935630)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207326(CHEMBL3891935)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207336(CHEMBL3932436)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207319(CHEMBL3949380)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207321(CHEMBL3908580)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207346(CHEMBL3961512)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207345(CHEMBL3944077)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207338(CHEMBL3935105)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50227631(2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207317(CHEMBL3955759)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207327(CHEMBL3987179)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207332(CHEMBL3976312)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207340(CHEMBL3934012)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207339(CHEMBL3925125)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207330(CHEMBL3952826)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207347(CHEMBL3947032)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
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