Found 143 Enz. Inhib. hit(s) with all data for entry = 50048224 
Affinity DataIC50: 1.20nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant full length His-tagged NUAK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant His-tagged FLT3 cytoplasmic domain (564 to 958 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant His-tagged KIT cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant full length His-tagged PDK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant His-tagged NTRK3 cytoplasmic domain (510 to 825 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of human recombinant full length His-tagged AURKB expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 167nMAssay Description:Inhibition of human full length wild type DYKDDDDK-tagged LRRK2 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha2/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 226nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Affinity DataIC50: 304nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Affinity DataIC50: 494nMAssay Description:Inhibition of human recombinant His-tagged NTRK1 cytoplasmic domain (441 to 796 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:Inhibition of human recombinant His-tagged FGFR2 cytoplasmic domain (403 to 822 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 605nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 627nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 658nMAssay Description:Inhibition of human recombinant full length GST/His-tagged CDK5/P25 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 668nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged SRC cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 692nMAssay Description:Inhibition of human recombinant full length His-tagged RPS6KA3 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 738nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 793nMAssay Description:Inhibition of human recombinant full length His-tagged CDK7/cyclin H/MNAT1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 818nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged LCK cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human recombinant GST-tagged CLK2 catalytic domain (137 to 498 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human recombinant GST-tagged TEK cytoplasmic domain (817 to 1101 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human recombinant full length His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human recombinant GST-tagged JAK2 cytoplasmic domain (809 to 1153 +9 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant GST-tagged INSR cytoplasmic domain (1011 to 1382 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human recombinant N-terminal His-tagged MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant GST-tagged MAP3K8 catalytic domain (30 to 397 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human recombinant full length His-tagged BMX cytoplasmic domain expressed in baculovirus expression systemMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human recombinant His-tagged KDR cytoplasmic domain (789 to 1356 residues) expressed in baculovirus expression systemMore data for this Ligand-Target Pair
