Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with all data for entry = 50048431
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50045004(9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-ox...)copy SMILEScopy InChI
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215357(CHEMBL6353)copy SMILEScopy InChI
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215365(CHEMBL6345)copy SMILEScopy InChI
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215546(CHEMBL268770)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215360(CHEMBL266458)copy SMILEScopy InChI
Affinity DataIC50: 3.07E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215358(CHEMBL204146)copy SMILEScopy InChI
Affinity DataIC50: 3.27E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215366(CHEMBL263076)copy SMILEScopy InChI
Affinity DataIC50: 4.46E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)copy SMILEScopy InChI
Affinity DataIC50: 4.99E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215356(CHEMBL6247)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215364(CHEMBL6335)copy SMILEScopy InChI
Affinity DataIC50: 9.42E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215361(CHEMBL6349)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215362(CHEMBL6336)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+6nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215363(CHEMBL6365)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+6nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215359(CHEMBL6364)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+6nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215547(Benzo[C]Chromen-6-One | CHEBI:86511 | CHEMBL6355)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+6nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25141DTPubMed