Compile Data Set for Download or QSAR
Found 50 Enz. Inhib. hit(s) with all data for entry = 50048561
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222105(CHEMBL92814)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222094(CHEMBL96305)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222105(CHEMBL92814)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222098(CHEMBL93161)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222096(CHEMBL92648)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222108(CHEMBL93028)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222094(CHEMBL96305)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222098(CHEMBL93161)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222101(CHEMBL329635)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222109(CHEMBL93059)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222084(CHEMBL327632)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222097(CHEMBL92851)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222096(CHEMBL92648)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222110(CHEMBL96629)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222100(CHEMBL329005)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222109(CHEMBL93059)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222093(CHEMBL178031)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222095(CHEMBL91864)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222099(CHEMBL93140)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222099(CHEMBL93140)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222095(CHEMBL91864)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222084(CHEMBL327632)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222108(CHEMBL93028)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222110(CHEMBL96629)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222098(CHEMBL93161)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222103(CHEMBL329792)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222094(CHEMBL96305)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222103(CHEMBL329792)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222105(CHEMBL92814)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222104(CHEMBL93462)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222110(CHEMBL96629)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222109(CHEMBL93059)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222101(CHEMBL329635)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222102(CHEMBL93910)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222097(CHEMBL92851)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222108(CHEMBL93028)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222106(CHEMBL93639)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222096(CHEMBL92648)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222103(CHEMBL329792)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222107(CHEMBL93650)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222097(CHEMBL92851)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222099(CHEMBL93140)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222084(CHEMBL327632)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222101(CHEMBL329635)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222093(CHEMBL178031)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222100(CHEMBL329005)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122372(1-(2,6-Dichloro-phenyl)-6-(2,4-difluoro-phenylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50222095(CHEMBL91864)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ688JPubMed