Found 21 Enz. Inhib. hit(s) with all data for entry = 50049024 TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.650nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.710nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.0700nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.240nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair
