Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for entry = 5666
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)copy SMILEScopy InChI
Affinity DataKi:  1.20nM IC50: 2.33nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM92503((2S)-2-[(2R)-2-(2,3-dihydro-1H-inden-1-yl)-3-sulfa...)copy SMILEScopy InChI
Affinity DataKi:  7.70nM IC50: 15.1nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM92502((2S)-2-[2-(5-bromo-2,3-dihydro-1H-inden-1-yl)-3-su...)copy SMILEScopy InChI
Affinity DataKi:  22.3nM IC50: 43.4nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM92500(Kelatorphan)copy SMILEScopy InChI
Affinity DataKi:  195nM IC50: 380nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM92501(Retrothiorphan)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM IC50: 1.00E+4nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nM IC50: 1.00E+5nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Homo sapiens (Human))
Pharmaleads

LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nM IC50: 1.00E+5nMAssay Description:Inhibitory assay against ECE-2.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P307KPubMed