Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 5676
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM92563(Hit compound, 4)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM67612(2-(2-pyridinyl)indene-1,3-dione | 2-(2-pyridyl)ind...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM92564(Hit compound, 5)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM92562(Hit compound, 3)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM52831(4-[(4-methylphenyl)hydrazo]-5-benzotriazolone | 4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM50651(2,6-bis(azanyl)-1,5-bis(chloranyl)anthracene-9,10-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM92565(Hit compound, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM92568(Hit compound, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center and Research Institute

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154FN2PubMed