Compile Data Set for Download or QSAR
Found 68 Enz. Inhib. hit(s) with all data for entry = 606
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4363((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...)copy SMILEScopy InChI
Affinity DataKi:  850nM IC50: 2.40E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4341(2-[(3,4,5-trihydroxyphenyl)methylidene]propanedini...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nM IC50: 3.00E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4340((3,4-Dihydroxy-5-methoxybenzylidene)malononitrile ...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nM ΔG°:  -32.0kJ/mole IC50: 6.00E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4301((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nM IC50: 1.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4360((3,4,5,B-Tetrahydroxybenzylidene)malononitrile | 2...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nM IC50: 1.35E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4338((3,5-Dihydroxybenzylidene)malononitrile | 2-[(3,5-...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nM ΔG°:  -28.3kJ/mole IC50: 3.70E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4339((3,4-Dihydroxybenzylidene)malononitrile | 2-[(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nM ΔG°:  -28.0kJ/mole IC50: 3.50E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4337(2-[(4-formylphenyl)methylidene]propanedinitrile | ...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nM ΔG°:  -26.6kJ/mole IC50: 6.00E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4380((2Z)-2-cyano-3-(2,5-dihydroxyphenyl)prop-2-enoic a...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nM IC50: 7.50E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4336(2-[(5-hydroxy-2-nitrophenyl)methylidene]propanedin...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nM ΔG°:  -26.1kJ/mole IC50: 9.60E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4352((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic a...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nM IC50: 7.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4351((2E)-2-cyano-3-(4-formylphenyl)prop-2-enoic acid |...)copy SMILEScopy InChI
Affinity DataKi:  4.70E+4nM IC50: 1.40E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4335(2-[(4-hydroxy-3-nitrophenyl)methylidene]propanedin...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+4nM ΔG°:  -24.4kJ/mole IC50: 1.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4334(2-[(3-bromo-4-hydroxy-5-methoxyphenyl)methylidene]...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nM ΔG°:  -24.3kJ/mole IC50: 1.53E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4333(2-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]...)copy SMILEScopy InChI
Affinity DataKi:  5.50E+4nM ΔG°:  -24.1kJ/mole IC50: 1.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4332(2-[(4-hydroxy-3-methoxyphenyl)methylidene]propaned...)copy SMILEScopy InChI
Affinity DataKi:  6.70E+4nM ΔG°:  -23.6kJ/mole IC50: 2.00E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4330(2-(2H-1,3-benzodioxol-5-ylmethylidene)propanedinit...)copy SMILEScopy InChI
Affinity DataKi:  1.17E+5nM ΔG°:  -22.2kJ/mole IC50: 3.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4329(2-[(3-hydroxyphenyl)methylidene]propanedinitrile |...)copy SMILEScopy InChI
Affinity DataKi:  1.23E+5nM ΔG°:  -22.1kJ/mole IC50: 3.75E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4328(4-(2,2-dicyanoeth-1-en-1-yl)benzoic acid | benzyli...)copy SMILEScopy InChI
Affinity DataKi:  1.43E+5nM ΔG°:  -21.7kJ/mole IC50: 4.30E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4327((2E)-3-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]prop-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nM ΔG°:  -21.6kJ/mole IC50: 4.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4326(2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedin...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nM ΔG°:  -21.6kJ/mole IC50: 4.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4325(2-[(3,5-di-tert-butyl-4-hydroxyphenyl)methylidene]...)copy SMILEScopy InChI
Affinity DataKi:  1.55E+5nM ΔG°:  -21.5kJ/mole IC50: 4.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4324(2-[(4-hydroxyphenyl)methylidene]propanedinitrile |...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+5nM ΔG°:  -21.4kJ/mole IC50: 5.60E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.65E+5nM IC50: 3.08E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4321(3-{[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]carbamoyl}p...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+5nM ΔG°:  -20.5kJ/mole IC50: 6.40E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4322((4-Morpholinobenzylidene)malononitrile | 2-{[4-(mo...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+5nM ΔG°: >-20.4kJ/mole IC50: 6.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4349((2E)-2-cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop...)copy SMILEScopy InChI
Affinity DataKi:  2.64E+5nM IC50: 7.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4320(2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]prop...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+5nM ΔG°:  -19.9kJ/mole IC50: 8.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4348((2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)prop-2-e...)copy SMILEScopy InChI
Affinity DataKi:  3.25E+5nM IC50: 8.00E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4354((2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)but-2-en...)copy SMILEScopy InChI
Affinity DataKi:  3.41E+5nM IC50: 1.10E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4356((2E)-2-cyano-N-(cyanomethyl)-3-(4-hydroxyphenyl)pr...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+5nM IC50: 6.25E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+5nM IC50: 1.20E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4317(2-[(4-methoxyphenyl)methylidene]propanedinitrile |...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: 1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4318(2-[(3,5-dimethoxyphenyl)methylidene]propanedinitri...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: 1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4319(2-[(4-fluorophenyl)methylidene]propanedinitrile | ...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+5nM ΔG°: >-19.2kJ/mole IC50: 1.25E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4343((2E)-2-cyano-3-(4-methoxyphenyl)prop-2-enoic acid ...)copy SMILEScopy InChI
Affinity DataKi:  8.33E+5nM IC50: 2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4344((2E)-2-cyano-3-(4-fluorophenyl)prop-2-enoic acid |...)copy SMILEScopy InChI
Affinity DataKi:  8.33E+5nM IC50: 2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4342((2E)-2-cyano-3-phenylprop-2-enoic acid | benzylide...)copy SMILEScopy InChI
Affinity DataKi:  8.50E+5nM IC50: 2.50E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4374((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+6nM IC50: 3.00E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4364((3Z)-2-amino-3-[(4-hydroxyphenyl)methylidene]prop-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4369((3Z)-2-amino-3-[(3-bromo-4,5-dihydroxyphenyl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4367((3Z)-2-amino-3-[(3,4,5-trihydroxyphenyl)methyliden...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4368((3Z)-2-amino-3-[(3,4-dihydroxy-5-methoxyphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4366((3Z)-2-amino-3-[(3,4-dihydroxyphenyl)methylidene]p...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM3973(N-[(E)-2-(2,5-dihydroxyphenyl)ethenyl]formamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4361((2E)-2-cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4365((3Z)-2-amino-3-[(4-hydroxy-3-nitrophenyl)methylide...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4382(benzylidenemalononitrile (BMN) deriv. 68 | cyano-N...)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4359(2-[hydroxy(4-hydroxyphenyl)methylidene]propanedini...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+5nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4331(2-[(3-hydroxy-4-methoxyphenyl)methylidene]propaned...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NHFPubMed
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