Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 6207
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)copy SMILEScopy InChI
Affinity DataKi:  59nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113750((2E)-N-[4-(2-Hydrazinylethyl)phenyl]-3-phenylprop-...)copy SMILEScopy InChI
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113753(N-[4-(2-Hydrazinylethyl)phenyl]-4-(1H-indol-3-yl)b...)copy SMILEScopy InChI
Affinity DataKi:  100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113745(4-(4-Fluorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  138nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113744(4-(4-Chlorophenyl)-N-[4-(2-hydrazinylethyl)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  156nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113748(2-(3-{[4-(2-Hydrazinylethyl)phenyl]amino}-3-oxopro...)copy SMILEScopy InChI
Affinity DataKi:  204nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113746(N-[4-(2-Hydrazinylethyl)phenyl]-4-(4-methoxyphenyl...)copy SMILEScopy InChI
Affinity DataKi:  207nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113752(N-[4-(2-Hydrazinylethyl)phenyl]-3-(1H-indol-3-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  210nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113749(3-(3-{[4-(2-Hydrazinylethyl)phenyl]amino}-3-oxopro...)copy SMILEScopy InChI
Affinity DataKi:  223nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113743(N-[4-(2-Hydrazinylethyl)phenyl]-5-phenylpentanamid...)copy SMILEScopy InChI
Affinity DataKi:  260nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113741(N-[4-(2-Hydrazinylethyl)phenyl]-3-phenylpropanamid...)copy SMILEScopy InChI
Affinity DataKi:  260nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113739(N-[4-(2-Hydrazinylethyl)phenyl]benzamide dihydroch...)copy SMILEScopy InChI
Affinity DataKi:  280nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113747(N-[4-(2-Hydrazinylethyl)phenyl]-4-(4-nitrophenyl)b...)copy SMILEScopy InChI
Affinity DataKi:  282nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113740(N-[4-(2-Hydrazinylethyl)phenyl]-2-phenylacetamide ...)copy SMILEScopy InChI
Affinity DataKi:  370nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)copy SMILEScopy InChI
Affinity DataKi:  820nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113751({3-[4-(Benxyloxy)phenyl]propyl}hydrazine dihydroch...)copy SMILEScopy InChI
Affinity DataKi:  900nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113755(N-Benzyl-N-[4-(2-hydrazinylethyl)phenyl]-4-phenylb...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113754(N-[4-(2-Hydrazinylethyl)phenyl]-N-methyl-4-phenylb...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113730((3-Phenylpropyl)hydrazine dihydrochloride salt (9c...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM50105417(CHEMBL1089 | Nardil | PHENELZINE | Phenethyl-hydra...)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113742(N-[4-(2-Hydrazinylethyl)phenyl]-4-phenylbutanamide...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113732([3-(4-Methoxyphenyl)propyl]hydrazine dihydrochlori...)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113737((3-Phenoxypropyl)hydrazine dihydrochloride salt (1...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113735((4-Phenylbutyl)hydrazine dihydrochloride salt (9h))copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113736((2-Phenoxyethyl)hydrazine dihydrochloride salt (10...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113731(1-Methyl-2-(3-phenylpropyl)hydrazine dihydrochlori...)copy SMILEScopy InChI
Affinity DataIC50: 4.67E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113728(1-Methyl-2-(2-phenylethyl)hydrazine dihydrochlorid...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113729(1,1-Dimethyl-2-(2-phenylethyl)hydrazine (9b))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113733(1-[3-(4-Methoxyphenyl)propyl]-2-methylhydrazine di...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113738(4-(3-Hydrazinylpropyl) morpholine (11))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States

LigandPNGBDBM113734(N’-[3-(4-Methoxyphenyl)propyl]acetohydrazide ...)copy SMILEScopy InChI
Affinity DatapH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14VFPubMed