Compile Data Set for Download or QSAR
Found 20 Enz. Inhib. hit(s) with all data for entry = 6856
TargetCyclin-dependent kinase 2 [C118L,A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [F80T](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [C118L](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [A144G](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [C118I](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [F80T](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [F80M](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [C118I](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [C118L,A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [A144G](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [F80M](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [C118L](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154577(K03859 (2))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:For IC50 measurements, a 384-well microtiter plate contained 8-point serial dilutions of inhibitors and 16-point serial dilutions of staurosporine as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MKHPubMed
TargetCyclin-dependent kinase 2 [C118L](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataKd:  18.6nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataKd:  50nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataKd:  15.4nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2 [C118L,A144C](Homo sapiens (Human))
University of Oxford

LigandPNGBDBM154576(K03861 (1))copy SMILEScopy InChI
Affinity DataKd:  9.70nMpH: 7.5 T: 2°CAssay Description:All ITC experiments were performed using a VP-ITC (Microcal, Northampton, MA) instrument at 10 or 15 °C in 50 mM HEPES, pH 7.5, 300 mM NaCl, and 1 mM...More data for this Ligand-Target Pair