Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 7030
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)copy SMILES
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)copy SMILES
Affinity DataIC50: 1nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)copy SMILES
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)copy SMILES
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)copy SMILES
Affinity DataIC50: 8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167513(US9073917, 10- comparative)copy SMILES
Affinity DataIC50: 9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167516(US9073917, 13- comparative)copy SMILES
Affinity DataIC50: 10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167516(US9073917, 13- comparative)copy SMILES
Affinity DataIC50: 11nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167509(US9073917, 6- comparative)copy SMILES
Affinity DataIC50: 13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)copy SMILES
Affinity DataIC50: 15nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167511(US9073917, 8- comparative)copy SMILES
Affinity DataIC50: 21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167513(US9073917, 10- comparative)copy SMILES
Affinity DataIC50: 22nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)copy SMILES
Affinity DataIC50: 23nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)copy SMILES
Affinity DataIC50: 68nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)copy SMILES
Affinity DataIC50: 72nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167511(US9073917, 8- comparative)copy SMILES
Affinity DataIC50: 102nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)copy SMILES
Affinity DataIC50: 107nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167509(US9073917, 6- comparative)copy SMILES
Affinity DataIC50: 109nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM60452(US9073917, 3-comparative)copy SMILES
Affinity DataIC50: 900nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)copy SMILES
Affinity DataIC50: 1.76E+3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM60452(US9073917, 3-comparative)copy SMILES
Affinity DataIC50: 3.80E+3nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent