Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 7156
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  0.800nM IC50: 4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  1.30nM IC50: 5nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  3nM IC50: 9nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  11nM IC50: 30nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  17nM IC50: 42nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  23nM IC50: 83nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  55nM IC50: 119nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)copy SMILEScopy InChI
Affinity DataKi:  110nM IC50: 230nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  120nM IC50: 250nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  120nM IC50: 260nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178102(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  550nM IC50: 1.10E+3nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nM IC50: 3.00E+3nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM IC50: 2.00E+4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)copy SMILEScopy InChI
Affinity DataKi: >3.75E+4nM IC50: 7.50E+4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178101(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nM IC50: 1.00E+5nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKd:  6nMpH: 8.5Assay Description:Isothermal titration calorimetry (ITC) was performed at 25 °C in a Nano ITC instrument (TA Instruments, USA). The cell was loaded with 25 μM PRM...More data for this Ligand-Target Pair