Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 7205
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM1773(US10280174, Comparative Compound 1 | US8476284, 4 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM181017(US9133201, 6)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97672(US8476284, 40 | US9133201, 10 | US9181263, 9 | US9...)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97677(US8476284, 7 | US8497277, 7 | US9133201, 7)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM1773(US10280174, Comparative Compound 1 | US8476284, 4 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97674(US8476284, 42 | US8497277, 8 | US9133201, 8)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM1773(US10280174, Comparative Compound 1 | US8476284, 4 ...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97671(US8476284, 39 | US9133201, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97670(US8476284, 38 | US9133201, 12)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97675(US8476284, 43 | US8497277, 15 | US9133201, 15 | US...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97678(US8476284, 9 | US8497277, 10 | US8497277, 9 | US91...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
PHARMACYCLICS, INC.

US Patent
LigandPNGBDBM97676(US8476284, 5 | US8497277, 5 | US9133201, 5)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4Assay Description:Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. Measurements were performed in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02KCUS Patent