Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for entry = 7534
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16313(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamothioy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50029207((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 430nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200222(2-(2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 450nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B1 [L301M](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 710nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM50012899((Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104022(MK319)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM104020(MK181)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+4nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4PFZPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Institut de Ge´ne´tique et de Biologie Mole´culaire et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+4nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4PFZPubMed