Compile Data Set for Download or QSAR
Found 119 Enz. Inhib. hit(s) with all data for entry = 7810
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220118(US9271961, EM1404)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.32E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  8.20E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  1.06E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337282(3-[N-(4-acetylphenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220115(US9271961, 13)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337286(3-[N-(4-tert-butylphenyl)amino]benzoic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM150758(2-(2-Hydroxyphenyl)-4H-chromen-4-one (3d) | US9271...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337287(3-[N-(4-methoxyphenyl)amino]benzoic acid | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337288(3-[N-(4-methylphenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337279(3-phenylamino benzoic acid | CHEMBL1682198 | US927...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)copy SMILEScopy InChI
Affinity DataIC50: 4.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)copy SMILEScopy InChI
Affinity DataIC50: 4.35E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220120(US9271961, Bimatoprost)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
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