Compile Data Set for Download or QSAR
Found 154 Enz. Inhib. hit(s) with all data for entry = 8031
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230228(US9340500, I-072)copy SMILEScopy InChI
Affinity DataKi:  21nM ΔG°:  -45.6kJ/mole IC50: 45nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230231(US9340500, I-075)copy SMILEScopy InChI
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 270nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230252(US9340500, I-096)copy SMILEScopy InChI
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 420nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230253(US9340500, I-097)copy SMILEScopy InChI
Affinity DataKi:  130nM ΔG°:  -40.9kJ/mole IC50: 430nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230229(US9340500, I-073)copy SMILEScopy InChI
Affinity DataKi:  160nM ΔG°:  -40.3kJ/mole IC50: 340nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230187(US9340500, I-031)copy SMILEScopy InChI
Affinity DataKi:  160nM ΔG°:  -40.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230174(US9340500, I-018)copy SMILEScopy InChI
Affinity DataKi:  169nM ΔG°:  -40.2kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230264(US9340500, I-108)copy SMILEScopy InChI
Affinity DataKi:  170nM ΔG°:  -40.2kJ/mole IC50: 540nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230172(US9340500, I-016)copy SMILEScopy InChI
Affinity DataKi:  191nM ΔG°:  -39.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230227(US9340500, I-071)copy SMILEScopy InChI
Affinity DataKi:  196nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230158(US9340500, I-002)copy SMILEScopy InChI
Affinity DataKi:  197nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230278(US9340500, I-122)copy SMILEScopy InChI
Affinity DataKi:  240nM ΔG°:  -39.3kJ/mole IC50: 780nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230219(US9340500, I-063)copy SMILEScopy InChI
Affinity DataKi:  251nM ΔG°:  -39.2kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230195(US9340500, I-039)copy SMILEScopy InChI
Affinity DataKi:  282nM ΔG°:  -38.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230256(US9340500, I-100)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -38.8kJ/mole IC50: 830nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230243(US9340500, I-087)copy SMILEScopy InChI
Affinity DataKi:  320nM ΔG°:  -38.6kJ/mole IC50: 710nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230203(US9340500, I-047)copy SMILEScopy InChI
Affinity DataKi:  320nM ΔG°:  -38.6kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230164(US9340500, I-008)copy SMILEScopy InChI
Affinity DataKi:  327nM ΔG°:  -38.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230194(US9340500, I-038)copy SMILEScopy InChI
Affinity DataKi:  352nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230170(US9340500, I-014)copy SMILEScopy InChI
Affinity DataKi:  355nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230177(US9340500, I-021)copy SMILEScopy InChI
Affinity DataKi:  379nM ΔG°:  -38.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230251(US9340500, I-095)copy SMILEScopy InChI
Affinity DataKi:  380nM ΔG°:  -38.1kJ/mole IC50: 970nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230246(US9340500, I-090)copy SMILEScopy InChI
Affinity DataKi:  380nM ΔG°:  -38.1kJ/mole IC50: 1.10E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230205(US9340500, I-049)copy SMILEScopy InChI
Affinity DataKi:  418nM ΔG°:  -37.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230182(US9340500, I-026)copy SMILEScopy InChI
Affinity DataKi:  427nM ΔG°:  -37.8kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230239(US9340500, I-083)copy SMILEScopy InChI
Affinity DataKi:  443nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230277(US9340500, I-121)copy SMILEScopy InChI
Affinity DataKi:  450nM ΔG°:  -37.7kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230279(US9340500, I-123)copy SMILEScopy InChI
Affinity DataKi:  450nM ΔG°:  -37.7kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230169(US9340500, I-013)copy SMILEScopy InChI
Affinity DataKi:  453nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230215(US9340500, I-059)copy SMILEScopy InChI
Affinity DataKi:  472nM ΔG°:  -37.6kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230185(US9340500, I-029)copy SMILEScopy InChI
Affinity DataKi:  519nM ΔG°:  -37.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230249(US9340500, I-093)copy SMILEScopy InChI
Affinity DataKi:  530nM ΔG°:  -37.3kJ/mole IC50: 1.40E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230247(US9340500, I-091)copy SMILEScopy InChI
Affinity DataKi:  560nM ΔG°:  -37.1kJ/mole IC50: 1.50E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230212(US9340500, I-056)copy SMILEScopy InChI
Affinity DataKi:  560nM ΔG°:  -37.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230241(US9340500, I-085)copy SMILEScopy InChI
Affinity DataKi:  590nM ΔG°:  -37.0kJ/mole IC50: 1.30E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230254(US9340500, I-098)copy SMILEScopy InChI
Affinity DataKi:  590nM ΔG°:  -37.0kJ/mole IC50: 1.90E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230207(US9340500, I-051)copy SMILEScopy InChI
Affinity DataKi:  590nM ΔG°:  -37.0kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230179(US9340500, I-023)copy SMILEScopy InChI
Affinity DataKi:  605nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230189(US9340500, I-033)copy SMILEScopy InChI
Affinity DataKi:  655nM ΔG°:  -36.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230222(US9340500, I-066)copy SMILEScopy InChI
Affinity DataKi:  662nM ΔG°:  -36.7kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230165(US9340500, I-009)copy SMILEScopy InChI
Affinity DataKi:  678nM ΔG°:  -36.6kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230186(US9340500, I-030)copy SMILEScopy InChI
Affinity DataKi:  701nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230208(US9340500, I-052)copy SMILEScopy InChI
Affinity DataKi:  707nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230220(US9340500, I-064)copy SMILEScopy InChI
Affinity DataKi:  713nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230166(US9340500, I-010)copy SMILEScopy InChI
Affinity DataKi:  714nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230180(US9340500, I-024)copy SMILEScopy InChI
Affinity DataKi:  755nM ΔG°:  -36.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230191(US9340500, I-035)copy SMILEScopy InChI
Affinity DataKi:  771nM ΔG°:  -36.3kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230230(US9340500, I-074)copy SMILEScopy InChI
Affinity DataKi:  780nM ΔG°:  -36.3kJ/mole IC50: 1.70E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230225(US9340500, I-069)copy SMILEScopy InChI
Affinity DataKi:  816nM ΔG°:  -36.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
SHIONOGI & CO., LTD.

US Patent
LigandPNGBDBM230200(US9340500, I-044)copy SMILEScopy InChI
Affinity DataKi:  844nM ΔG°:  -36.1kJ/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TR3US Patent
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