Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for entry = 8162
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235646(Hydroxyethylamine (HEA))copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235642((E)-1-(2,4-dihydroxyphenyl)-3-(2,3-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50203985((E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235644((E)-1-(2,4-dihydroxyphenyl)-3-(2,6-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235643((E)-1-(2,4-dihydroxyphenyl)-3-(2,5-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235645((E)-1-(2,4-dihydroxyphenyl)-3-(3,5-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.08E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50042949((E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50027475((E)-1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235634((E)-1-(2,4-dihydroxyphenyl)-3-(2-methoxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50140168((E)-1-(2,4-dihydroxyphenyl)-3-(3-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 8.03E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50360514((E)-1-(2,4-dihydroxyphenyl)-3-(2-chlorophenyl)-2-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235640((E)-1-(3,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235639((E)-1-(2,6-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235641((E)-1-(3,5-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235638((E)-1-(2,3-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 2.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235636((E)-1-(3-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)copy SMILEScopy InChI
Affinity DataIC50: 3.04E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50027481((E)-1-(2,5-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235637((E)-1-(4-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)copy SMILEScopy InChI
Affinity DataIC50: 5.81E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50027665((E)-1-(2,4-dihydroxyphenyl)-3-(2-allyloxyphenyl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM86002((E)-1-phenyl-3-(2-hydroxyphenyl)-2-propen-1-one (8...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM50015607((E)-1-(2-hydroxyphenyl)-3-(2-hydroxyphenyl)-2-prop...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

LigandPNGBDBM235635((E)-1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)-2-pr...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2TCJPubMed