TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.0510nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.289nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.307nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.320nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.325nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.375nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.429nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.452nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.801nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.815nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.870nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.872nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 0.899nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.02nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.17nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.23nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.25nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.32nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.38nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.43nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.58nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.71nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 2.98nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 3.11nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 4.58nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 7.33nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 27.2nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 63.5nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 471nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 495nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 572nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 738nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.15E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.91E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 3.18E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 4.98E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.13E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.48E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 5.96E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 6.65E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 8.11E+3nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Hoffmann-La Roche Inc.
US Patent
Hoffmann-La Roche Inc.
US Patent
Affinity DataIC50: 1.03E+4nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair