Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for entry = 862
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 0.0192nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294479(N-(3-((2-((6-(4-methylpiperazin-1-yl)pyridin- 3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.0365nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM50159347(CHEMBL3787662 | US9586965, Cpd 1)copy SMILEScopy InChI
Affinity DataIC50: 0.0366nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294480(N-(3-((2-((3-fluoro-4-(4-methylpiperazin-1- yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 0.0911nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 0.196nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294479(N-(3-((2-((6-(4-methylpiperazin-1-yl)pyridin- 3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.362nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 0.365nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294480(N-(3-((2-((3-fluoro-4-(4-methylpiperazin-1- yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 0.399nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM50159347(CHEMBL3787662 | US9586965, Cpd 1)copy SMILEScopy InChI
Affinity DataIC50: 0.579nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 4.97nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294480(N-(3-((2-((3-fluoro-4-(4-methylpiperazin-1- yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 501nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM50159347(CHEMBL3787662 | US9586965, Cpd 1)copy SMILEScopy InChI
Affinity DataIC50: 570nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294479(N-(3-((2-((6-(4-methylpiperazin-1-yl)pyridin- 3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM50159347(CHEMBL3787662 | US9586965, Cpd 1)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294480(N-(3-((2-((3-fluoro-4-(4-methylpiperazin-1- yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.27E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
ACEA BIOSCIENCES INC.

US Patent
LigandPNGBDBM294479(N-(3-((2-((6-(4-methylpiperazin-1-yl)pyridin- 3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, specific kinase/substrate pairs along with required cofactors were prepared in reaction buffer. Compounds were delivered into the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0VZ1US Patent