Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for entry = 8714
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM414420((R)-7-[4-(2-ethoxycarbonyl-2-hydroxyethyl)oxy-2-me...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331841((S)-7-[4-(3-cyano-2-hydroxypropyl)oxy-2-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331840((R)-7-[4-(3-cyano-2-hydroxypropyl)oxy-2-methoxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331839((S)-7-[4-(2,4-dihydroxybutyl)oxy-2-methoxyphenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331836((S)-8-(5-fluoro-2-methylphenoxymethyl)-7-[4-(2-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331837((R)-8-(5-fluoro-2-methylphenoxymethyl)-7-[4-(2-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331842(7-[4-(3-t-butoxycarbonyl-2-hydroxypropyl)oxy-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331844(8-(5-fluoro-2-methylphenoxymethyl)-7-(5-hydroxy-2-...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent
TargetInterleukin-6(Homo sapiens (Human))
SANTEN PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM331843(8-(5-fluoro-2-methylphenoxymethyl)-7-(5-hydroxymet...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:1) The subcultured HCE-T was recovered and the cells were seeded at 2.0×104 cells/0.1 mL/well in a 96-well flat bottom culture plate.2) After culturi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X350TPUS Patent