Compile Data Set for Download or QSAR
Found 43 Enz. Inhib. hit(s) with all data for entry = 8775
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419129(3CLpro inhibitor 6h)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419130(3CLpro inhibitor 7h)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419126(3CLpro inhibitor 7c)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419128(3CLpro inhibitor 7e)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419124(3CLpro inhibitor 6c)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419123(3CLpro inhibitor 7a)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419127(3CLpro inhibitor 6e)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419127(3CLpro inhibitor 6e)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419128(3CLpro inhibitor 7e)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419126(3CLpro inhibitor 7c)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419124(3CLpro inhibitor 6c)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419121(3CLpro inhibitor 6a)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419130(3CLpro inhibitor 7h)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419133(BDBM429386 | GC376)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419129(3CLpro inhibitor 6h)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419133(BDBM429386 | GC376)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419123(3CLpro inhibitor 7a)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419121(3CLpro inhibitor 6a)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419127(3CLpro inhibitor 6e)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419128(3CLpro inhibitor 7e)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419126(3CLpro inhibitor 7c)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419124(3CLpro inhibitor 6c)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419130(3CLpro inhibitor 7h)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419133(BDBM429386 | GC376)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419129(3CLpro inhibitor 6h)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419123(3CLpro inhibitor 7a)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Wichita State University

LigandPNGBDBM419121(3CLpro inhibitor 6a)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:The expression and purification of the 3CLpro of MERS-CoV and SARS-CoV were performed by a standard method described previously by our lab (11, 19, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419124(3CLpro inhibitor 6c)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419124(3CLpro inhibitor 6c)copy SMILEScopy InChI
Affinity DataEC50:  250nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419128(3CLpro inhibitor 7e)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419129(3CLpro inhibitor 6h)copy SMILEScopy InChI
Affinity DataEC50:  900nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419130(3CLpro inhibitor 7h)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataEC50:  40nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419123(3CLpro inhibitor 7a)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419131(3CLpro inhibitor 6j | 3CLpro inhibitor 7j)copy SMILEScopy InChI
Affinity DataEC50:  800nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetOrf1a protein(MERS-CoV)
Wichita State University

LigandPNGBDBM419133(BDBM429386 | GC376)copy SMILEScopy InChI
Affinity DataEC50:  900nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Wichita State University

LigandPNGBDBM419127(3CLpro inhibitor 6e)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Some compounds in the 6a to 6k and 7a to 7k series were also investigated for their antiviral activity against the replication of MERS-CoV, FIPV, or ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D52PubMed