Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for entry = 9145
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191770(US10669227, Compound 7 | US11608309, Compound 7 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445062(US10669227, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445059(US10669227, Compound 5 | US11608309, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445064(US10669227, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445058(US10669227, Compound 1 | US11608309, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445061(US10669227, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445062(US10669227, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191763(US10669227, Compound Curcumin | US11608309, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM191770(US10669227, Compound 7 | US11608309, Compound 7 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent
TargetCollagenase 3(Homo sapiens (Human))
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

US Patent
LigandPNGBDBM445060(US10669227, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5X14US Patent