Compile Data Set for Download or QSAR
Found 70 Enz. Inhib. hit(s) with all data for entry = 9200
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448544(N-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448727(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-5- y...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448683(N-(2-(4-(thiazol-5-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448695(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448663(N-(2-(4-(oxazol-5-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 0.760nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448673(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448662(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448675(N-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448664(5-(tetrahydro-2H-pyran-4-yl)-N-(2-(4-(thiazol-4- y...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448697(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448726(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448715(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448647(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448696(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448661(N-(2-(4-(oxazol-2-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448729(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448717(N-(2-(4-(isoxazol-5-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448682(N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448674(N-(5-chloro-2-(4-(oxazol-4-ylmethyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448723(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448718(US10696661, Compound 65)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448698(5-methyl-N-(2-(4-((5-methylfuran-2-yl)methyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 10.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448670(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448672(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)copy SMILEScopy InChI
Affinity DataIC50: 11.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448684(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 12.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448667(5-(pyridin-4-yl)-N-(2-(4-(thiazol-4-ylmethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 13.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448681(N-(2-(4-(thiazol-2-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448548(5-methyl-N-(2-(4-((furan-2-yl)methyl)piperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 17.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448704(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5-(trif...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448657(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 21.4nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448687(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5- (tri...)copy SMILEScopy InChI
Affinity DataIC50: 21.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448699(N-(2-(4-(furan-3-ylmethyl)piperazin-1-yl)-5- (trif...)copy SMILEScopy InChI
Affinity DataIC50: 21.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448685(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448680(N-(5-chloro-2-(4-(furan-2-ylmethyl)piperazin-1- yl...)copy SMILEScopy InChI
Affinity DataIC50: 27.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448668(5-(pyridin-4-yl)-N-(2-(5-(thiazol-2-ylmethyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 27.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448693(N-(2-(4-(1H-imidazol-4-ylmethyl)piperazin-1-yl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448693(N-(2-(4-(1H-imidazol-4-ylmethyl)piperazin-1-yl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448690(N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5- ...)copy SMILEScopy InChI
Affinity DataIC50: 31.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448700(N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 32.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448722(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 33.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448725(N-(2-(4-(isoxazol-4-ylmethyl)piperazin-1-yl)-5- (t...)copy SMILEScopy InChI
Affinity DataIC50: 35.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448621(N-(2-(4-(thiazol-5-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 39.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448691(US10696661, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 60.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448574(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 62.4nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448733(N-(2-(4-((1H-indol-3-yl)methyl)piperazin-1-yl)-5- ...)copy SMILEScopy InChI
Affinity DataIC50: 74.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448714(N-(2-(4-((1H-pyrazol-4-yl)methyl)piperazin-1-yl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 75.9nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448592(N-(2-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-5- (tr...)copy SMILEScopy InChI
Affinity DataIC50: 79.8nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448706(N-(2-(4-(oxazol-4-ylmethyl)piperazin-1-yl)-5-(trif...)copy SMILEScopy InChI
Affinity DataIC50: 83.1nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448545(N-(2-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 88.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate Limited

US Patent
LigandPNGBDBM448665(US10696661, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 104nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B635RUS Patent
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