Compile Data Set for Download or QSAR
Found 51 Enz. Inhib. hit(s) with all data for entry = 925
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299114((6S,8S)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299113((6S,8S)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...)copy SMILES
Affinity DataIC50: 0.520nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299149((6S,8R)-6-(4-(2- (3- (difluoromethyl) azetidin-1- ...)copy SMILES
Affinity DataIC50: 0.580nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299143((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 0.670nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299144((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299141((6R,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(4-(...)copy SMILES
Affinity DataIC50: 0.980nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299148(6-(2,6-difluoro- 4-(2-(3- (fluoromethyl) azetidin-...)copy SMILES
Affinity DataIC50: 1nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299131((6S,8R)-7-(2,3- difluoro-2- methylpropyl)-6- (4-(2...)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299158(3,5-difluoro-4- ((6S,8R)-7-(2- fluoro-2- methylpro...)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299111(US10125135, Example 1)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299119((6S,8R)-7-((l-fluorocyclopropyl)methyl)-6-(5-(2-(3...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299122((6S,8R)-7-(2,2- difluoropropyl)-6- (4-(2-(3- (fluo...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299136((6S,8R)-7-(2,2- difluoropropyl)-6- (2-fluoro-4-(2-...)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299142((6R,8R)-6-(4- (2-(3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299112((6S,8R)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299152((6S,8R)-7-(2,2- difluoropropyl)- 6-(5-(2-(3- (fluo...)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299139((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299133((6S,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299147(6-(2,6-difluoro- 4-(2-(3- (fluoromethyl) azetidin-...)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299118((6S,8R)-7-(2,2-difluoroethyl)-6-(4-(2-(3-(fluorome...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299131((6S,8R)-7-(2,3- difluoro-2- methylpropyl)-6- (4-(2...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299161((6S,8R)-6-(3-fluoro-5-(2-(3-(fluoromethyl)azetidin...)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299160((6S,8R)-6-(5-(2-(3-(fluoromethyl)azetidin-1-yl)eth...)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299154((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 2.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299129((6S,8R)-7-(2,3- difluoropropyl)- 6-(4-(2-(3- (fluo...)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299129((6S,8R)-7-(2,3- difluoropropyl)- 6-(4-(2-(3- (fluo...)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299155((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299138((6S,8R)-6-(2- fluoro-4-(2-(3- (fluoromethyl) azeti...)copy SMILES
Affinity DataIC50: 2.60nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299145((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 2.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299150(2-((6S,8R)-7-((1- fluorocyclo- propyl)methyl)- 8-m...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299134((6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methox...)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299123((6S,8R)-6-(4-(2- (3-(fluoromethyl) azetidin-1- yl)...)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299115((6S,8R)-7-(2-fluoro-2-methylpropyl)-6-(4-(2-(3-(fl...)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299125(2,2-difluoro-3- ((6S,8R)-6-(4-(2- (3-(fluoromethyl...)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299124((6S,8R)-6-(4-(2- (3-(fluoromethyl) azetidin-1- yl)...)copy SMILES
Affinity DataIC50: 3.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299135((6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methox...)copy SMILES
Affinity DataIC50: 3.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299137(2,2-difluoro-3- ((6S,8R)-6-(2- fluoro-4-(2-(3- (fl...)copy SMILES
Affinity DataIC50: 3.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299145((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...)copy SMILES
Affinity DataIC50: 3.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299159((6S,8R)-7-(2,2- difluoroethyl)-6- (3-fluoro-5-(2-(...)copy SMILES
Affinity DataIC50: 4.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299127((6S,8R)-7-(2- fluoro-3- methoxy-2- methylpropyl)-6...)copy SMILES
Affinity DataIC50: 4.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299157((6S,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(6-(...)copy SMILES
Affinity DataIC50: 4.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299126((6S,8R)-7-(2,2- difluoro-3- methoxypropyl)- 6-(4-(...)copy SMILES
Affinity DataIC50: 5.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299120((6S,8R)-6-(4-(2-(3-(fluoromethyl)azetidin-1-yl)eth...)copy SMILES
Affinity DataIC50: 5.80nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299162((6S,8R)-7-(2,2-difluoroethyl)-6-(5-(2-(3-(fluorome...)copy SMILES
Affinity DataIC50: 5.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299153((6-chloro-4-methoxypyridin-3-yl)methanol | US10125...)copy SMILES
Affinity DataIC50: 6.60nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299156(7-(2,2- difluoroethyl)- 6-(5-(2-(3- (fluoromethyl)...)copy SMILES
Affinity DataIC50: 7.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299121((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-6-(5-(2-(...)copy SMILES
Affinity DataIC50: 7.90nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299140((6R,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(4-(...)copy SMILES
Affinity DataIC50: 9.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299151((6S,8R)-6-(5-(2- (3-(fluoromethyl) azetidin-1- yl)...)copy SMILES
Affinity DataIC50: 9.40nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
TargetEstrogen receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM299127((6S,8R)-7-(2- fluoro-3- methoxy-2- methylpropyl)-6...)copy SMILES
Affinity DataIC50: 9.70nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B04KWUS Patent
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