Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 9826
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491842(N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-isobutyl- p...)copy SMILES
Affinity DataIC50: 900nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491847(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(3,3,3-trif...)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491846(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2,2-trif...)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491859(US10975066, Example 24)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491840(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-cyclopropyl...)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491843(N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-(2-methoxy-...)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491845(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2-difluo...)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491844(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2-fluoroet...)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491839(N-(1-(1H-indol-3- yl)hexan-2-yl)-2-(4- isopropylpi...)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491853(N-(2-(1H-indol-3- yl)ethyl)-N-butyl- 2-(4-methyl- ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491850(N-(1-(1H-indol- 3-yl)hexan-2-yl)- 2-(cis-3,4,5- tr...)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491838(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-ethylpipera...)copy SMILES
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491854(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (3-(fluorometh...)copy SMILES
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491858(US10975066, Example 23)copy SMILES
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491851(N-(1-(1H-indol- 3-yl)-5-methyl- hexan-2-yl)-2-(4- ...)copy SMILES
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491841(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(tert-butyl...)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491849(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (3,3,4-trimeth...)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491848(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (3,4-dimethyl-...)copy SMILES
Affinity DataIC50: 1.60E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491857(US10975066, Example 22)copy SMILES
Affinity DataIC50: 1.70E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491856(N-(2-(1H-indol-3- yl)-1-phenylethyl)- 2-(4-methyl-...)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491852(N-(1-cyclopentyl- 2-(1H-indol-3- yl)ethyl)-2-(4- m...)copy SMILES
Affinity DataIC50: 2.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491855(N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (8-methyl-3,8-...)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491862(US10975066, Example 66)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491861(US10975066, Example 64)copy SMILES
Affinity DataIC50: 4.60E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
UCB Biopharma SRL

US Patent
LigandPNGBDBM491860(US10975066, Example 63)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9F6XUS Patent