Found 35 Enz. Inhib. hit(s) with Target = '1,3-beta-glucan synthase' and Ligand = 'BDBM50478215' Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of FKS1 from Candida krusei 98 isolateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 13.4nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 20% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 50% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Neosartorya fumigata)
UMDNJ-New Jersey Medical School
Curated by ChEMBL
UMDNJ-New Jersey Medical School
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase EMFR-S678P mutant from Aspergillus fumigatus assessed as incorporation of [3H]glucoseMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of Candida glabrata isolate 234 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659V mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of Candida glabrata isolate 51916 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p P667T mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of Candida glabrata isolate 42031 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666E mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 264nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 507nMAssay Description:Inhibition of Candida glabrata isolate 41400 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666G mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 608nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 698nMAssay Description:Inhibition of Candida glabrata isolate 42997 1,3-beta-D-glucan synthase Fks1p F625S mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 756nMAssay Description:Inhibition of Candida glabrata isolate 21900 1,3-beta-D-glucan synthase Fks1p D632G mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 845nMAssay Description:Inhibition of Candida glabrata isolate 3169 1,3-beta-D-glucan synthase Fks1p D632E mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of Candida glabrata isolate 41026 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659S mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of FKS1 T2080K mutant from Candida krusei 100 isolateMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 4.99E+3nMAssay Description:Inhibition of Candida glabrata isolate 5847 1,3-beta-D-glucan synthase Fks1p S629P mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
University of Medicine and Dentistry of New Jersey
Curated by ChEMBL
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of Candida glabrata isolate 3830 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p S663P mutantMore data for this Ligand-Target Pair
